home - Ashraf Mohammad Mahmoud

Prof.  Ashraf Mohamed Mohamed Mahmoud

Professor 

Professor 
College of Pharmacy 
Pharmaceutical Chemistry

Specialty: Pharmaceutical Analytical Chemistry
Mobile No. 0550204707
Email: amsayed@nu.edu.sa  and a.mahmoud2007@yahoo.com

0175428888
info@nu.edu.sa

المؤهلات العلمية

1- Ph.D. in Pharmaceutical Analytical Chemistry. “Radioimmunoassay and radiochemical procedure for determination of cutaneous uptake and metabolism of sex steroid hormones” from Freie University, Berlin (Germany), May 2005.
2. M.Sc. in Pharmaceutical Analytical Chemistry.  “Analysis of some antifungal drugs in pure forms and in pharmaceutical preparations”.   Assiut University, Egypt.   June   1998.
3. B.Sc. in Pharmaceutical Science. Very Good with Degree of Honour.  Assiut University, Egypt.  May, 1992.

الخبرات

  1. Supervisor of the development and quality unit at the college of pharmacy 2016-2019.
  2. Department coordinator of the pharmaceutical chemistry department, college of pharmacy, Najran University, KSA.  Sept., 2013  to  date
  3. College coordinator since Juli 2012 to 2019,
  4. Head of academic office for the medical colleges Oct. 2012 to 2016,
  5. Professor in the Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Najran University, KSA.  Sept., 2011  to  Sept., 2016   
  6. Academic Advisor of the college of pharmacy since 2012 to 2018         
  7. Associate Professor in the Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Najran University, KSA.  Sept., 2011  to  Sept., 2016 
  8. Associate Professor in the Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Egypt.  Sept., 2010  to  Sept., 2016 
  9. Lecturer in the Department of Pharmaceutical Analytical Chemistry,  Faculty of Pharmacy, Assiut University, Egypt.   Jul. 31st  , 2005  - Jul. 31st  2010
  10. Assistant professor in the Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Saudi Arabia. Sept. 6th 2006 – Jul.15th  2009.
  11. Assistant Lecturer, in the Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Egypt.,   Aug., 15th 1998 –Jul., 30th 2005.
  12. Demonstrator, in the same department.  Jan., 15th 1993 – Aug., 15th 1998.

التخصصات والمهارات

Teaching Experiences

  1. External Evaluator and Examiner in Faculties of Pharmacy of Cairo, Alexandria, El-minia, El-Mansoura, Al-Azhar, Russian and El-Nahda-Beny Swief universities.
  2. Teaching of quantitative analytical chemistry courses for undergraduate pharmacy students in Assiut, Al-Azhar, King Saud and Najran Universities.
  3. Teaching of instrumental (Chromatography [HPLC, GC, HPTLC], electrophoresis, UV-VIS spectrophotometry, fluorimetry, chemoluminescence and electrochemistry) analysis courses for undergraduate pharmacy students in Assiut, King Saud and Najran Universities.
  4. Teaching of quality control & pharmaceutical analysis course for undergraduate clinical pharmacy students in Assiut and Najran Universities.
  5. Teaching of advanced spectroscopic methods (UV-VIS, IR, Mass, 1H-NMR, and atomic spectroscopy) course for undergraduate clinical pharmacy and postgraduate students in Assiut University.
  6. Teaching of Advanced spectroscopic analysis and extraction & clean up methodology courses for Ph.D. pharmacy students in Assiut University.
  7. Teaching of Advanced instrumental analysis and kinetics methods in pharmaceutical analysis courses for M.Sc. pharmacy students in King Saud University

Experiences in the field of continuous development of the educational process and academic accreditation
  1. Department coordinator of the pharmaceutical chemistry for all aspects concerning the development and quality at the college of pharmacy, Sept., 2013  to  date
  2. Head of academic office for the medical colleges Oct. 2012 to 2016,
  3. Academic Advisor of the college of pharmacy since 2012 to 2018
  4. Participation in establishing the internal quality assurance system in the college of pharmacy, Najran University, KSA.  Sept., 2013  to  2016
  5. Participation in the preparation of Najran University for the exploratory visit from the NCAAA 1438
  6. Participation in the preparation of Najran University for the final accreditation visit from the NCAAA November 2018
  7. Continuous development and qualification for the academic accreditation of college of Pharmacy in Najran University (2019-2021) and Final Visit on December, 5-8 2021.
  8. Participation in establishing the internal quality assurance system  in the faculty of pharmacy Assiut university 2005-2006
  9. Continuous development and qualification for the academic accreditation of the faculty of Pharmacy in Assiut University (2009-2010).
  10. Member of the Quality assurance unit of the faculty of pharmacy, Assiut University.
  11. Participation in the preparation of the faculty of pharmacy, Assiut University for the simulation visit from the quality assurance system at Assiut University on 19-22 April 2010
  12. Participation in the preparation of the faculty of pharmacy, Assiut University for the exploratory visit from the NAQAA on 9-12 May 2010
  13. Participation in the preparation of the faculty of pharmacy, Assiut University for the Final accreditation  visit from the NAQAA on 2-5 May 2011.
  14. Contribution to spreading the culture of quality in the college of pharmacy at Najran University via several workshops as:
  • More than thirty seminars and workshops within Najran University
  • More than fifty meetings of the quality assurance unit at the college
  • Preparing more than 10 manuals on quality issues
  • Presenting and discussing quality issues to the College Council

SUPERVISION OF THESES
  1. Supervision of the M. Sc. Thesis “Analytical Methods for H2-Receptor Antagonists” Faculty of Pharmacy, Assiut University, Egypt. (finished, 2007)
  2. Supervision of M. Sc. thesis “New Selctive Analytical Methods for Determination of Gemifloxacin in pharmaceutical preparation and biological fluids” Faculty of Pharmacy,  Assiut University, Egypt. (finished, 2014)
  3. Supervision of Ph.D. thesis.  “Analysis of some pharmaceutical drugs and biologically active compounds using capillary electrochromatography” Faculty of Pharmacy, Assiut University, Egypt. (finished, 2014)
  4. Supervision of Ph.D. thesis “New HPLC and votammetric methods for determination of certain hypolipidemic drugs” Faculty of Pharmacy, Assiut University, Egypt. (finished, 2018)

Research and Technology Projects in the Fields of Interest
  1. “In vitro validated alternatives to animal experiments” research project which is financially supported by the German Validation Center for Alternative Methods (ZEBET; WK 1-1328-170), Berlin, Germany, 2005. The project evaluate the formulation effects on percutaneous absorption of different skin models; reconstructed epidermis and full-thickness skin models for reducing the need for animal experiments and the risks for patients receiving a new drug or new formulation.
  2. “Formal large scale validation study comparing the uptake of chemicals by reconstructed epidermis to uptake in human and animal skin to set up a standard protocol for the use of reconstructed epidermis in routine skin absorption tests” research project which is financially supported by the German Ministry of Education and Research (BEO 031288-1/4/6), Berlin, Germany, 2003.
  3. “Development of Sensitive Immunoanalytical Technique for 2'-Deoxycytidine as a Potential Prognostic Marker for Breast Cancer Chemotherapy.” research project which is financially supported by the Research Center, College of Pharmacy, King Saud University, Saudi Arabia (grant No. CPRC. 183).
  4. “Synthesis and Investigation of Some Amantadine Derivatives as Hepatic Delivery System to Enhance its Activity against HCV.” research project which is financially supported by the Research Center, College of Pharmacy, King Saud University, Saudi Arabia (grant No. CPRC. 181).
  5. “Novel analytical approach for reducing the consumption of organic solvents in the charge transfer-based spectrophotometric analysis.” research project which is financially supported by the Research Center, College of Pharmacy, King Saud University, Saudi Arabia (grant No. CPRC. 225).
  6. “Novel high-throughput kinetic spectrophotometric for determination of pentoxifylline hydrochloride and its metabolites in plasma and pharmaceuticals.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/14/062)
  7.  “Novel accurate and sensitive analytical approach for determination of omeprazole in combined pharmaceutical formulations and human plasma using advanced nanomaterials-based sensors and 2,3-dichloro-naphthoquinone and 2,3,5,6-tetrabromo-1,4-benzoquinone reagents. ” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/15/063)
  8. “Decoration of S, N co-doped graphene quantum dots with ?-aminothiophenol functionalized AuNPs for molecular imprinted sensing of sofosbuvir in real samples.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/032)
  9. “One pot synthesis of AuPdPt trimetallic nanohybrid decorated reduced graphene oxide nanosheets for ultrasensing of anti-convulsant drug retigabine.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/055)
  10. “Simultaneous analysis of mycophenolate mofetil and tacolimus using multiple layers of MWCNTs and a novel Cu-ADPPI MOFs modified pencil graphite electrode.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/039)
  11. “Facile fabrication of a novel 3D rose like lanthanium doped zirconia decorated reduced graphene oxide nanosheets: An efficient electro-catalyst for electrochemical reduction of futuristic anti-cancer drug salinomycin during pharmacokinetic study.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/090)
  12. “A novel imidazole derived colorimetric sensor for sequential detection of copper (II) and sulphide ions in aqueous solutions and biosamples.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/091)

الدورات التدربية

Training workshop on “Teaching with technology” Assiut University, Egypt, July 2005.
Training workshop on “Problem solving and decision making” Assiut University, Sept 2005.
 Training workshop on “Skills of the active connection” Assiut University, Egypt, Sept 2005.
Training workshop on “Modern trends in teaching” Assiut University, Egypt, Oct. 2005.
Training workshop on “Skills of the active presentation” Assiut University, Egypt, Oct. 2005.
Training workshop on “Course and curriculum design” Assiut University, Egypt, Oct. 25th, 2005.
Workshop on (Nano Research at Universities), Riyadh, Saudi Arabia, Oct 28-29th , 2007
Training workshop on “Strategic Planning” Assiut University, Egypt, Aug. 8th, 2009.
Training workshop on “Exams Systems and Students’ Evaluation” NCAAA workshop in Holiday In, Najran, Dec. 2011.
Training workshop on “Writing Scientific Research Project” Assiut University, Feb. 2012.
Training workshop on “Quality Standards in Teaching Process 1” Assiut University, May 2013.
Training workshop on “Quality standards in infrastructure support” Holiday In, Najran, NCAAA workshop on 2-3 April 2013.
Training workshop on “Preparation of Annual program report” Najran University, NCAAA workshop on 14-15 May 2013
Training workshop on “Exams Systems and Students’ Evaluation” NCAAA workshop in Holiday In, Najran, Sept. 2013
Training workshop on “Program design under the National Qualifications Framework” NCAAA workshop in Holiday In, Najran, 7-8 Oct 2013
Training workshop on Quality assurance and program evaluation. Holiday In, Najran, NCAAA workshop, Oct-Nov. 2013.
Training workshop on “Preparing the program specification according to the standards of NCAAA” on 18-19 Nov. 2013
Training workshop on Quality indicators and benchmarks. Holiday In, Najran, NCAAA workshop, Nov. 2013.
Training workshop on “Preparing the course report according to the standards of NCAAA” on 17-18 Dec. 2013
Training workshop on Preparation of self-study report, Holiday In, Najran, NCAAA workshop, Dec. 22-23,   2013.
Training workshop on “Modern Strategies in Teaching” Assiut University, Juli. 25-26th 2014.
Training workshop on “Quality Standards in Teaching Process” Juli. 25-26th 2014.
Training workshop on “Assessment of program and course learning outcomes” 11-12 Dec 2014.
Training workshop on SAQF learning outcomes. NCAAA place, Riyadh, Saudi Arabia, 2019

الأبحاث العلمية

RESEARCH AND TECHNOLOGY PROJECTS
  1. “In vitro validated alternatives to animal experiments” research project which is financially supported by the German Validation Center for Alternative Methods (ZEBET; WK 1-1328-170), Berlin, Germany, 2005. The project evaluate the formulation effects on percutaneous absorption of different skin models; reconstructed epidermis and full-thickness skin models for reducing the need for animal experiments and the risks for patients receiving a new drug or new formulation.
  2. “Formal large scale validation study comparing the uptake of chemicals by reconstructed epidermis to uptake in human and animal skin to set up a standard protocol for the use of reconstructed epidermis in routine skin absorption tests” research project which is financially supported by the German Ministry of Education and Research (BEO 031288-1/4/6), Berlin, Germany, 2003.
  3. “Development of Sensitive Immunoanalytical Technique for 2'-Deoxycytidine as a Potential Prognostic Marker for Breast Cancer Chemotherapy.” research project which is financially supported by the Research Center, College of Pharmacy, King Saud University, Saudi Arabia (grant No. CPRC. 183).
  4. “Synthesis and Investigation of Some Amantadine Derivatives as Hepatic Delivery System to Enhance its Activity against HCV.” research project which is financially supported by the Research Center, College of Pharmacy, King Saud University, Saudi Arabia (grant No. CPRC. 181).
  5. “Novel analytical approach for reducing the consumption of organic solvents in the charge transfer-based spectrophotometric analysis.” research project which is financially supported by the Research Center, College of Pharmacy, King Saud University, Saudi Arabia (grant No. CPRC. 225).
  6. “Novel high-throughput kinetic spectrophotometric for determination of pentoxifylline hydrochloride and its metabolites in plasma and pharmaceuticals.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/14/062)
  7.  “Novel accurate and sensitive analytical approach for determination of omeprazole in combined pharmaceutical formulations and human plasma using advanced nanomaterials-based sensors and 2,3-dichloro-naphthoquinone and 2,3,5,6-tetrabromo-1,4-benzoquinone reagents. ” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/15/063)
  8. “Decoration of S, N co-doped graphene quantum dots with ?-aminothiophenol functionalized AuNPs for molecular imprinted sensing of sofosbuvir in real samples.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/032)
  9. “One pot synthesis of AuPdPt trimetallic nanohybrid decorated reduced graphene oxide nanosheets for ultrasensing of anti-convulsant drug retigabine.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/055)
  10. “Simultaneous analysis of mycophenolate mofetil and tacolimus using multiple layers of MWCNTs and a novel Cu-ADPPI MOFs modified pencil graphite electrode.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/039)
  11. “Facile fabrication of a novel 3D rose like lanthanium doped zirconia decorated reduced graphene oxide nanosheets: An efficient electro-catalyst for electrochemical reduction of futuristic anti-cancer drug salinomycin during pharmacokinetic study.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/090)
  12. “A novel imidazole derived colorimetric sensor for sequential detection of copper (II) and sulphide ions in aqueous solutions and biosamples.” research project which is financially supported by the Deanship of Scientific Research, Najran University. Project Code (nu/mid/16/091)
SUPERVISION OF THESES
  1. Supervision of the M. Sc. Thesis “Analytical Methods for H2-Receptor Antagonists” Faculty of Pharmacy, Assiut University, Egypt. (finished, 2007)
  2. Supervision of M. Sc. thesis “New Selctive Analytical Methods for Determination of Gemifloxacin in pharmaceutical preparation and biological fluids” Faculty of Pharmacy,  Assiut University, Egypt. (finished, 2014)
  3. Supervision of Ph.D. thesis.  “Analysis of some pharmaceutical drugs and biologically active compounds using capillary electrochromatography” Faculty of Pharmacy, Assiut University, Egypt. (finished, 2014)
  4. Supervision of Ph.D. thesis “New HPLC and votammetric methods for determination of certain hypolipidemic drugs” Faculty of Pharmacy, Assiut University, Egypt. (finished, 2018)
 
 All publications (73) are published internationally and the majority of them are of high quality (Q1-Q2) papers
      https://scholar.google.com/citations?hl=ar&user=17tyhHcAAAAJ
 
  1. Salwa R El-Shabouri, Kamla M Emara, Pakinaz Y Khashaba, Ashraf M Mohamed: Charge-transfer complexation for spectrophotometric assay of certain imidazole antifungal drugs. Anal. Lett., 31 (1998)1367-1385.
  2. Ashraf M Mohamed: Analysis of some antifungal drugs in pure forms and in pharmaceutical preparations. Assiut University
  3. PY Khashaba, SR El-Shabouri, KM Emara, AM Mohamed: Analysis of some antifungal drugs by spectrophotometric and spectrofluorimetric methods in different pharmaceutical dosage forms. J. Pharm. Biomed. Anal., 22 (2000)363-76.
  4. S Schreiber, A Mahmoud, MK Rübbelke, M Schaller, HC Korting, E Schmidt, M Liebsch, M Sch?fer-Korting: Validation study on percutaneous absorption via human skin models. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 369, 8-8, 2004
  5. A Mahmoud, A Haberland, M Dürrfeld, D Heydeck, S Wagner, M Sch?fer-Korting: Cutaneous estradiol permeation, penetration and metabolism in pig and man. Skin Pharmacology and Physiology, 18 (2005)27-35.
  6. S Schreiber, A Mahmoud, A Vuia, MK Rübbelke, E Schmidt, M Schaller, H Kand?rov?, A Haberland, UF Sch?fer, U Bock, HC Korting, M Liebsch, M Sch?fer-Korting: Reconstructed epidermis versus human and animal skin in skin absorption studies. Toxicology in Vitro, 19 (2005)813-822.
  7. A Mahmoud: Radioimmunoassay and radiochemical procedure for determination of cutaneous uptake and metabolism of sex steroid hormones. Freie University, Berlin, Germany, 2005
  8. Ibrahim A. Darwish, Ashraf M. Mahmoud, Abdel-Rahman A. Al-Majed: generic simple enzyme immunoassay approach to avert small molecule immobilization problems on solid phases. Application to the determination of tobramycin in serum. Talanta, 72 (2007)1322-1328.
  9. Ashraf Mahmoud, Simone Lombardi Borgia, Sylvia Schreiber, Wolfgang Mehnert, Burkhard Kleuser, Monika Sch?fer-Korting: Human Reconstructed Skin Models for Absorption Testing: Comparison of hydrocortisone and testosterone formulations. Controlled Release Society conference, 2007
  10. Ibrahim A. Darwish, Samiha A Hussein, Ashraf M Mahmoud, Ahmed I Hassan: Sensitive indirect spectrophotometric method for determination of H2-receptor antagonists in pharmaceutical formulations. Int. J. Biomed. Sci., 2007, 3: 123-130.
  11. Hanaa M. Abdel-Wadood, Niveen A. Mohamed, Ashraf M. Mahmoud: Validated spectrofluorometric methods for determination of amlodipine besylate in tablets. Spectrochimica Acta Part A, 70 (2008) 564-570.
  12. Ibrahim A. Darwish, Ashraf M. Mahmoud, Nasr Y. Khalil: Non-extractive procedure and pre-column derivatization with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole for trace determination of trimetazidine in plasma by HPLC with fluorescence detection J. AOAC Int., 91 (2008)1037-1044.
  13. Ibrahim A. Darwish, Samiha A Hussein, Ashraf M Mahmoud, Ahmed I Hassan: Spectrophotometric determination of H2-receptor antagonists via their oxidation with cerium (IV). Spectrochimica Acta Part A, 69 (2008)33-40.
  14. Monika Sch?fer-Korting, Ashraf Mahmoud, Simone Lombardi Borgia, Barbara Brüggener, Burkhard Kleuser, Sylvia Schreiber, Wolfgang Mehnert: Reconstructed Epidermis and Full-Thickness Skin for Absorption Testing: Influences of the Vehicles Used on Steroid Permeation. ATLA, 36 (2008) 441-452.
  15. Ibrahim A. Darwish, Samiha A Hussein, Ashraf M Mahmoud, Ahmed I Hassan: A sensitive spectrophotometric method for the determination of H2-receptor antagonists by means of N-bromosuccinimide and p-aminophenol. Acta Pharmaceutica, 58 (2008) 87-97.
  16. Ibrahim A. Darwish, Ashraf M. Mahmoud, Abdel-Rahman A. Al-Majed, Tarek Abo-ElFadl, Nasr Y. Khalil: A Highly Sensitive Enzyme Immunoassay For Evaluation Of 2'-Deoxycytidine Plasma Level As A Prognostic Marker For Breast Cancer Chemotherapy, Anal. Chim. Acta, 632 (2009) 266-271.
  17. Ibrahim A. Darwish, Abdel-Rahman A. Al-Majed, Ashraf M. Mahmoud, Nasr Y. Khalil: New non-extractive and highly sensitive HPLC method for determination of paroxetine in plasma after offline precolumn derivatization with 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole. J. AOAC Int., 92 (2009)1-8.
  18. Ashraf M. Mahmoud, New Sensitive Kinetic Spectrophotometric Methods for Determination of Omeprazole in Dosage Forms. Int.J.Anal.Chem,2009 (2009)1-11 (Published online, doi:10.1155/2009/307045).
  19. Ashraf M. Mahmoud, Nasr Y. Khalil, Ibrahim A. Darwish, Tarek Aboul-Fadl: Selective spectrophotometric and spectrofluorometric methods for the determination of amantadine hydrochloride in capsules and plasma via derivatization with 1,2-naphthoquinone-4-sulphonate. Int. J. Ana.l Chem., 2009 (2009) (Published online, 8 pages, doi: 10.1155/2009/810104).
  20.  Ashraf M. Mahmoud, Ibrahim A. Darwish, Nasr Y. Khalil: Fluorometric study for the reaction between sertraline and 7-chloro-4-nitrobenzo-2-oxa-1,3-diazole: kinetics, mechanism and application for the determination of sertraline in tablets. J Fluorescence 20 (2010) 607–613.
  21. Ibrahim Darwish, Samiha Abdel-Rahman, Ashraf Mahmoud, Ahmed Hassan: “Spectral investigation and analytical application  of the vinylamino-substituted haloquinone derivatives of nizatidine and ranitidine” Int. J. Res. Pharm. Sci., 1 (2010) 1-7.
  22. Nasr Y. Khalil, Ashraf M. Mahmoud, Ibrahim A. Darwish, Abdul-Rahman A. Al-Majed: “Highly Sensitive HPLC Method with Automated Co-Sense System and Fluorescence Detection for Determination of Sertraline in Human Plasma” Chromatographia 72 (2010).
  23. Ashraf M. Mahmoud, Nasr Y. Khalil, Ibrahim A. Darwish, Tarek Aboul-Fadl: selective and sensitive methods for the determination of amantadine. Analytical Chemistry: Methods and Applications
  24. Ibrahim Darwish, Samiha Abdel-Rahman, Ashraf Mahmoud, Ahmed Hassan: “N-bromosuccinimide/fluorescein system for spectrophotometric determination of H2-receptor antagonists in their dosage forms” Int. J. Res. Pharm. Sci., 1 (2010) 86-93.
  25. Ibrahim A. Darwish, Tarek Aboul-Fadl, Nasr Y. Khalil, Ashraf M. Mahmoud,  Abdul-Rahman M. Al-Obaid: New Sensitive HPLC Method for Evaluation of the Pharmacokinetics of New Amantadine Prodrugs as Hepatic Delivery Systems to Enhance its Activity against HCV. Int. J. Res. Pharm. Sci., 1 (2010) 151-157.
  26. Ibrahim A. Darwish, Ashraf M. Mahmoud, Abdul-Rahman A. Al-Majed: Novel analytical approach for reducing the consumption of organic solvents in the charge transfer-based spectrophotometric analysis of losartan potassium. Int. J. Res. Pharm. Sci., 1 (2010) 151-157.
  27. Tarek Aboul-Fadl, Ashraf M. Mahmoud, Nasr Y. Khalil,  Ibrahim A. Darwish, Abdul-Rahman M. Al-Obaid: Evaluation of the Pharmacokinetics of New Amantadine Prodrugs as Hepatic Delivery Systems to Enhance its Activity against HCV. THE AMERICAN CHEMICAL SOCIETY 237 (2009) 355-355. 2009/3/22
  28. Ibrahim A. Darwish, Ashraf M. Mahmoud, Abdul-Rahman A. Al-Majed: Novel analytical approach for reducing the consumption of organic solvents in the charge transfer-based spectrophotometric analysis:  Application in the analysis of certain antihypertensive drugs. Acta Pharmaceutica, 60 (2010).
  29. Badraddin M.H. Al-Hadiya, Ashraf M. Mahmoud: Gemifloxacin Comprehensive Profile, Analytical Profile of Drug Substances, Excipients and Related Methodology, Vol. 39, 2011.
  30. Ashraf M. Mahmoud, Hanaa M. Abdel-Wadood, Niveen A. Mohamed: Kinetic Spectrophotometric Method for Determination of Amilodipine Besylate in its Pharmaceutical Tablets. J. Pharm. Anal., 2 (2012)
  31. Ashraf M. Mahmoud, Salwa R. El-Shabouri, Noha N. Atia, Wesam M. El-koussi: Novel simple HPTLC approach to avert pretreatment of plasma samples: Application to the determination of gemifloxacin mesylate using fluorescence detection. Assiut University 7th Pharmaceutical Sciences Conference, Assiut, Egypt, Marsh 14-15th , 2012
  32. Noha N. Atia, Ashraf M. Mahmoud, Salwa R. El-Shabouri, Wesam M. El-koussi: Two validated spectrofluorometric methods for determination of Gemifloxacin mesylate in tablets and human plasma. Int. J. Ana.l Chem., 2013  (Published online, 11 pages, http://dx.doi.org/10.1155/2013/137279).
  33. Marwa Fathy Bakr Ali, Naoya Kishikawa, Kaname Ohyama, Horria Abdel-Mageed Mohamed, Hanaa Mohamed Abdel-Wadood, Ashraf Mohamed Mohamed, Naotaka Kuroda, Chromatographic determination of aliphatic aldehydes in humanserum after pre-column derivatization using 2,2_-furil, a novelfluorogenic reagent. J. Chromatogr. A 1300 (2013) 199– 203.   
  34. Marwa F Ali, Naoya Kishikawa, Kaname Ohyama, Horria A. Mohamed, Hanaa M. Abdel-Wadood, Ashraf M Mahmoud, Takahiro Imazato, Yukitaka Ueki, Mitsuhiro Wada, Naotaka Kuroda: Chromatographic determination of low-molecular mass unsaturated aliphatic aldehydes with peroxyoxalate chemoluminescence detection after fluorescence labeling with4-(N,N-dimethyl-aminosulfonyl)-7-hydrazino-2,1,3-benzoxadiazole.
    J. Chromatography B,     953-954 (2014)147-152.
  35. Wesam M El-Koussi, Noha N Atia, Ashraf M Mahmoud, Salwa R El-Shabouri: HPTLC method for direct determination of gemifloxacin mesylate in human plasma. J. Chromatography B, 967 (2014) 98-101.
  36. Ashraf M Mahmoud, Noha N Atia, Salwa R El-Shabouri, Wesam M El-Koussi: Flow injection analysis for quantitative determination of gemifloxacin mesylate in pharmaceutical preparations and human plasma. Assiut University 9th International Pharmaceutical Sciences Conference, Assiut, Egypt, 12-13th March 2014, p. 93.
  37. Sameh Ahmed, Ashraf M Mahmoud: A novel salting-out assisted extraction coupled with HPLC- fluorescence detection for trace determination of vitamin K homologues in human plasma. Talanta 144 (2015) 480-487.
  38. Ashraf M Mahmoud, Noha N Atia, Salwa R El-Shabouri, Wesam M El-Koussi: Development and Validation of Stability Indicating HPTLC Assay for Determination of Gemifloxacin Mesylate in Dosage Forms. American J Anal Chem 6 (2015) 85-97.
  39. Ashraf M Mahmoud, Sameh Ahmed: A Validated High-Throughput Fluorometric Method for Determination of Omeprazole in Quality Control Laboratory via Charge Transfer Sensitized Fluorescence. J Fluorescence. 26 (2016) 521-526. DOI 10.1007/s10895-015-1737-4
  40. Ashraf M. Mahmoud, Saad A AlQahtani: Spectrophotometric Study for the Reaction of Pentoxifylline Hydrochloride with 1, 2-Naphthoquinone-4-Sulphonate: Kinetics, Mechanism and Application for Development of High-throughput Kinetic Microwell Assay for Pentoxifylline in Quality Control Laboratory. American J Anal Chem 7 (2016) 179-191.
  41. Wesam M El-Koussi, Noha N Atia, Ashraf M Mahmoud: Spectrofluorometric Methods for Determination of Gemifloxacin Mesylate. Book: 20/11/2013; Lambert Academic Publishing, ISBN: 978-3-659-4905-4.
  42. Saad A AlQahtani, Samer S. Abu-Alrub, Ashraf M. Mahmoud: Adsorption of food coloring allura red dye (E129) from aqueous solutions using activated carbon. International Journal of Food and Allied Sciences, 2017, 3(1): 10-19
  43. Saad A AlQahtani, Ashraf M. Mahmoud, Samer S. Abu-Alrub: Novel analytical study for the charge-transfer reactions of omeprazole with 2,3-dichloro-naphthoquinone and 2,3,5,6-tetrabromo1,4-benzoquinone: Application for the development of microwell assay of omeprazole. Journal of Advances in Chemistry, 2018, 15(2): 6099-6115
  44. Mohamed M. El-Wekil, Ashraf M. Mahmoud, Saad A. Alkahtani, Adel A. Marzouk, Ramadan Ali, A facile synthesis of 3D NiFe2O4 nanospheres anchored on a novel ionic liquid modi?ed reduced graphene oxide for electrochemical sensing of ledipasvir: Application to human pharmacokinetic study. Biosensors and Bioelectronics 109 (2018) 164–170
  45. Mohamed M. El-Wekil, Saad A. Alkahtani, Hassan R Ali, Ashraf M. Mahmoud, Advanced sensing nanomaterials based carbon paste electrode for simultaneous electrochemical measurement of esomeprazole and diclofenac sodium in human serum and urine samples. Journal of Molecular Liquids 262(2018) 495–503
  46. Mohamed M. El-Wekil, Ashraf M. Mahmoud, Adel A. Marzouk, Saad A. Alkahtani, Ramadan Ali, A novel molecularly imprinted sensing platform based on MWCNTs/AuNPs decorated 3D starfish like hollow nickel skeleton as a highly conductive nanocomposite for selective and ultrasensitive analysis of a novel pan-genotypic inhibitor velpatasvir in body fluids. Journal of Molecular Liquids 271 (2018) 105–111
  47. Ashraf M. Mahmoud & Mohamed M. El-Wekil & Mater H. Mahnashi & Marwa F. B. Ali & Saad A. Alkahtani, Modification of N,S co-doped graphene quantum dots with p-aminothiophenol-functionalized gold nanoparticles for molecular imprint-based voltammetric determination of the antiviral drug sofosbuvir. Microchimica Acta 186 (2019) 617
  48. Mater H. Mahnashi & Ashraf M. Mahmoud & Saad A. Alkahtani, Decoration of S, N co-doped graphene quantum dots functionalized gold nanoparticles for molecular imprinted sensing of sofosbuvir in real samples. THE AMERICAN CHEMICAL SOCIETY 285 (2019).
  49. Saad A. Alkahtani, Mohamed M. El-Wekil, Ashraf M. Mahmoud, Mater H. Mahnashi and Mohamed Oraby, One Pot Synthesis of AuPdPt Trimetallic Nanohybrid Decorated Reduced Graphene Oxide Nanosheets for Ultrasensing of Anti-Convulsant Drug Retigabine (Ezogabine). Journal of The Electrochemical Society, 166 (2019) H521-H526.
  50. Mater H. Mahnashi, Ashraf M. Mahmoud, Saad A. Alkahtani, Ramadan Ali, and Mohamed M. El-Wekil, Facile fabrication of a novel disposable pencil graphite electrode for simultaneous determination of promising immunosuppressant drugs mycophenolate mofetil and tacrolimus in human biological fluids. Analytical and Bioanalytical Chemistry, (2019) doi:10.1007/s00216-019-02245-8
  51. Saad A. Alkahtani, Ashraf M. Mahmoud, Mater H. Mahnashi, Ramadan Ali, and Mohamed M. El-Wekil, Facile fabrication of a novel 3D rose like lanthanum doped zirconia decorated reduced graphene oxide nanosheets: An efficient electro-catalyst for electrochemical reduction of futuristic anti-cancer drug salinomycin during pharmacokinetic study. Biosensors and Bioelectronics 150 (2020) 111849
  52. Ashraf M. Mahmoud, Saad A Alkahtani, Bandar A Alyami, and Mohamed M. El-Wekil. Dual-recognition molecularly imprinted aptasensor based on gold nanoparticles decorated carboxylated carbon nanotubes for highly selective and sensitive determination of histamine in different matrices. Analytica Chimica Acta, 1133 (2020), 58-65
  53. Mater H. Mahnashi, Ashraf M. Mahmoud, Saad A. Alkahtani, Ramadan Ali, and Mohamed M. El-Wekil, A novel imidazole derived colorimetric and fluorometric chemosensor for bifunctional detection of copper (II) and sulphide ions in environmental water samples. Spectrochimica Acta Part A, 81 (2020) 117846
  54. Ashraf M. Mahmoud, Mater H. Mahnashi, Saad A. Alkahtani, and Mohamed M. El-Wekil, Nitrogen and sulfur co-doped graphene quantum dots/nanocellulose nanohybrid for electrochemical sensing of anti-schizophrenic drug olanzapine in pharmaceuticals and human biological fluids. International journal of biological macromolecules. 165 (2020) 2030-2037.
  55. Ali O.Alqarni, Saad A.Alkahtani, Ashraf M. Mahmoud, Mohamed M.El-Wekil, Design of “Turn On” fluorometric nanoprobe based on nitrogen doped graphene quantum dots modified with ?-cyclodextrin and vitamin B6 cofactor for selective sensing of dopamine in human serum, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Elsevier, 248 (2021), 119180
  56. Ashraf M. Mahmoud, Mater H. Mahnashi, and Mohamed M. El-Wekil, Indirect differential pulse voltammetric analysis of cyanide at porous copper based metal organic framework modified carbon paste electrode: Application to different water samples. Talanta, 221 (2021) 121562
  57.  Mater H. Mahnashi, Ashraf M. Mahmoud, Saad A. Alkahtani, and Mohamed M. El-Wekil, Simultaneous electrochemical detection of azithromycin and hydroxychloroquine based on VS2 QDs embedded N, S @graphene aerogel/cCNTs 3D nanostructure, Microchemical Journal, Elsevier, 163, 105925, January, 2021
  58. Saad A. Alkahtani, Ashraf M. Mahmoud, Mater H. Mahnashi, Ali O. AlQarni, Yahya S. A. Alqahtani, Mohamed M. El-Wekil, Facile one pot sonochemical synthesis of layered nanostructure of ZnS NPs/rGO nanosheets for simultaneous analysis of daclatasvir and hydroxychloroquine, Microchemical Journal, Elsevier, 164, 105972, January, 2021
  59. Ashraf M. Mahmoud, Mater H. Mahnashi, Khalid Alhazzani, Alanazi AZ, Mohammad M. Algahtani, Ali Alaseemd, Bandar A. Alyami, Ali O. AlQarni, Mohamed M. El-Wekil, Nitrogen doped graphene quantum dots based on host guest interaction for selective dual readout of dopamine, Spectrochimica Acta part A, Elsevier, 252, 119516, February, 2021
  60. Mater H.Mahnashi, Ashraf M. Mahmoud, A Z Alanazi, Khalid Alhazzani, Saleh A. Alanazi, Mohammed M. Alanazi, Mohamed M.El-Wekil, A novel design and facile synthesis of nature inspired poly (dopamine-Cr3+) nanocubes decorated reduced graphene oxide for electrochemical sensing of flibanserin, Microchemical Journal, Elsevier, 164, 106020, 2021
  61. Bandar A.Alyami, Ashraf M .Mahmoud, Saad A. Alkahtani, Mohamed M. El-Wekil, NiFe2O4 nanospheres functionalized with 2-(2, 4-Dihydroxyphenyl)-3, 5, 7-trihydroxychromen-4-one for selective solid-phase microextraction of aluminium, Talanta, Elsevier, 226, 122167, January, 2021
  62. Mater H. Mahnashi, Ashraf M. Mahmoud, Saad A. Alkahtani, and Mohamed M. El-Wekil, Ivermectin detection using Ag@ B, S co-doped reduced graphene oxide nanohybrid. Journal of Alloys and Compounds, 871 (2021) 159627
  63. Mater H. Mahnashi, Ashraf M. Mahmoud, Khalid Alhazzani, A. Z. Alanazi,, Ali M Alaseem, Mohammad M. Algahtani  and Mohamed M. El-Wekil, Ultrasensitive and selective molecularly imprinted electrochemical oxaliplatin sensor based on a novel nitrogen-doped carbon nanotubes/Ag@cu MOF as a signal enhancer and reporter nanohybrid. Microchimica Acta 188 (2021) 731
  64. Mater H Mahnashi, Ashraf M Mahmoud, Khalid Alhazzani, AZ Alanazi, Mohammad M Algahtani, Ali Mohammed Alaseem, Yahya SA Alqahtani, Mohamed M El-Wekil. Enhanced molecular imprinted electrochemical sensing of histamine based on signal reporting nanohybrid. Microchemical Journal, Elsevier, 168, 106439, 2021
  65. Mater H Mahnashi, Samer S Abu-Alrub, Saad A Alahmed, Ashraf M Mahmoud, Ali O Alqarni. BIO MONITORING OF LEAD, ZINC, COPPER, CADMIUM AND IRON HEAVY METALS IN SOIL AND PLANT USING ATOMIC ABSORPTION SPECTROSCOPY IN NAJRAN AREA, SAUDI ARABIA. FRESENIUS ENVIRONMENTAL BULLETIN, 30 (2021) 1868-1872.
  66. Ashraf M. Mahmoud, Mater H Mahnashi, Samer S Abu-Alrub Saad A. Alkahtani, Mohamed M. El-Wekil. Indirect differential pulse voltammetric determination of fluoride ions at carbon paste electrode modified with porous and electroactive Fe3+/Fe2+ based-metal organic frameworks type MIL-101(Fe). Journal of The Electrochemical Society, 168 (2021) 126525.
  67. Ashraf M. Mahmoud, Saad A. Alkahtani, and Mohamed M. El-Wekil, Highly selective and sensitive electrochemical determination of cysteine based on complexation with gold nanoparticle–modifed copper?based metal organic frameworks. Anal Bioanal Chem (2022). Doi. 10.1007/s00216-021-03852-0
  68. Ashraf M. Mahmoud, Mater H Mahnashi, Adel Al Fatease, Mahmoud A.H. Mostafa, Mohamed M. El-Wekil, Ramadan Ali. Fluorometric and electrochemical dual-mode detection of toxic flavonoid rutin based on new nitrogen and sulfur co-doped carbon dots: Enhanced selectivity based on masking the interfering flavonoids with BSA complexation. Journal of Food Composition and Analysis 108(2022) 104428.
  69. Ashraf M. Mahmoud, Saad A. Alkahtani, and Mohamed M. El-Wekil, Electrochemical sensing of copper-chelator D-pencillamine based on complexation with gold nanoparticles modified copper based-metal organic frameworks. Food Composition and Analysis (2022).
  70. Samer S Abu-Alrub. Ashraf M. Mahmoud, Mater H Mahnashi, DEVELOPMENT OF SPECTROFLUOROMETRIC METHOD FOR DETERMINATION OF CARMINE DYE (E120) IN MARKETED JUICES PRODUCTS IN SAUDI ARABIA
  71. Ashraf M. Mahmoud, Mohamed M. El-Wekil, Ramadan Ali, Hany A. Batakoushy, Reem Y. Shahin, Double-signal quantification of amoxicillin based on interaction with 4-aminoantipyrine at copper and nitrogen co-doped carbon quantum dots as an artificial nanozyme. Microchimica Acta 189 (2022) 183
  72. Yahya S. Alqahtani, Ashraf M. Mahmoud, Mohamed M. El-Wekil. Bifunctional nanoprobe for dual-mode detection based on blue emissive iron and nitrogen co-doped carbon dots as a peroxidase-mimic platform. Talanta 253 (2023) 124024
  73. Ashraf M. Mahmoud, Bandar A. Alyami, Mater H Mahnashi, F.M. Alshareef, Yahia S. AlQahtani, Mohamed M. El-Wekil. Facile fabrication of a superior electrochemical sensor with anti-fouling properties for sensitive and selective determination of glutathione. Microchemical Journal, Elsevier, 187 (2023) 108419
  74. Ashraf M. Mahmoud, Mater H Mahnashi, F.M. Alshareef, Mohamed M. El-Wekil. Functionalized vanadium disulfide quantum dots as a novel dual-mode sensor for ultrasensitive and highly selective determination of rutin. Microchemical Journal, Elsevier, 187 (2023) ------

Courses 

Pharmacytical Analytical Chemistry 
Pharamceutical Organic Chemistry 
Instrumental Anlysis 

الساعات المكتبية

الوصف

  8-9 9-10 10-11 11-12 12-1 1-2
الأحد
Sunday		  

 PHCH 212 Lect.

PHCH 213 Lect.

      
الاثنين
Monday

Department meeting

Office hour

Office hour

      
الثلاثاء
Tuesday		  

PHCH 212 Lect.

PHCH 213 Lect.

      
الأربعاء
Wednesday

Research group meeting

Office hour

Office hour

      
الخميس
Thursday