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الاسم الرباعي: د. محمد مرعي سعد الشهراني

المسمى الوظيفي: عضو هيئة تدريس

المرتبة العلمية: أستاذ مساعد
الكلية: كلية العلوم الطبية التطبيقية
القسم: علوم المختبرات الإكلينيكية

وصف عام: خبرة تعليمية واسعة وخبرة متنوعة في مجال اللغة الإنجليزية ومجال الكيمياء الحيوة الإكلينيكية. حاصل على شهادة في اللغة الإنجليزية المستوى المتقدم من جامعة بيتسبرغ، الولايات المتحدة الأمريكية، خلال العامين 2012 و2013، مما زاد من قدرتي على التواصل بلغة انجليزية بطلاقة وفهم عميق للغة. كما أكملت دورة اللغة الإنجليزية التمهيدية في جامعة مانشستر بالمملكة المتحدة في عام 2014، حيث تعززت مهاراتي في اللغة الإنجليزية وتحسن.

حاصل على درجة البكالوريوس في علوم المختبرات الطبية من جامعة الملك خالد في المملكة العربية السعودية في الفترة من 2004 إلى 2009، حيث أطلعت على أساسيات وتقنيات هذا المجال.

حاصل على درجة الماجستير في الكيمياء الحيوية السريرية من جامعة مانشستر بتقدير التميز خلال العامين 2014 و2015. في هذه الفترة، قمت بالتعمق في دراسة الكيمياء الحيوية وتطبيقاتها السريرية.

وفيما بعد، أكملت رحلتي الأكاديمية بالحصول على درجة الدكتوراه في التحليل البيوكيميائي لتعزيز امتصاص اليود المشع في سرطان الغدد الصماء من جامعة برمنجهام في المملكة المتحدة خلال الفترة من 2016 إلى 2021. تركزت أبحاثي على المجالات المتقدمة في علم الأحياء الجزيئي والكيمياء الحيوية، وهي الخبرة التي ساهمت في تطوير مهاراتي البحثية والتحليلية بشكل كبير.

0175428888
info@nu.edu.sa

المؤهلات العلمية

 
درجة البكالوريوس في علوم المختبرات الطبية من جامعة الملك خالد في المملكة العربية السعودية في الفترة من 2009.
 شهادة في اللغة الإنجليزية المستوى المتقدم من جامعة بيتسبرغ، الولايات المتحدة الأمريكية، خلال العامين 2013.
 دورة اللغة الإنجليزية التمهيدية في جامعة مانشستر بالمملكة المتحدة في عام 2014.
 درجة الماجستير في الكيمياء الحيوية السريرية من جامعة مانشستر بالمملكة المتحدة في عام 2015. 
درجة الدكتوراه في التحليل البيوكيميائي لتعزيز امتصاص اليود المشع في سرطان الغدد الصماء من جامعة برمنجهام بالمملكة المتحدة في عام 2021.

الخبرات

  1. تدريب لمدة عام شمل: استقبال المختبر، بنك الدم، أمراض الدم، علم الأحياء الدقيقة، علم المناعة، الجودة، الكيمياء الحيوية، علم الأنسجة المرضية.
  2. خبرة معملية في جامعة مانشستر، المملكة المتحدة.
  3. خبرة معملية في معهد البحوث الطبية الحيوية بجامعة برمنجهام، المملكة المتحدة
  4. خبرة تزيد عن عشر سنوات في مجال التعليم الجامعي.
  5. خبرة في أساسيات الجودة والاعتماد الأكاديمي.
  6. رئيس قسم علوم المختبرات الإكلينيكية.

التخصصات والمهارات

التخصصات:

  1. الكيمياء الحيوية السريرية: خبرة في دراسة التركيب والوظيفة الحيوية للجزيئات والخلايا في الجسم البشري.
  2. البحوث البيوكيميائية: مهارات في إجراء البحوث العلمية لفحص الجوانب الكيميائية للظواهر الحيوية.
  3. تكنولوجيا المعلومات الطبية: قدرة على استخدام البرمجيات والأنظمة المعلوماتية لإدارة البيانات الطبية والتقارير.
  4. التحليل البيولوجي: خبرة في استخدام أدوات التحليل المختلفة لدراسة العناصر الحيوية والجزيئات في الأنظمة البيولوجية.
المهارات:
  1. البحث والتحليل: القدرة على إجراء البحوث العميقة وتحليل البيانات بدقة.
  2. الاتصال: مهارات تواصل لشرح الأفكار العلمية بوضوح وفهم جيد للجمهور المستهدف.
  3. إدارة المشاريع: الخبرة في تنظيم المشاريع البحثية وإدارة الوقت والموارد بكفاءة.
  4. اللغات: إجادة اللغة الإنجليزية والقدرة على التواصل مع جمهور دولي.
  5. القيادة: القدرة على تحفيز الفرق وإدارة الطلاب أو الزملاء في المشاريع البحثية.

الدورات التدربية

  1. دورة تدريبية الكترونية بعنوان "المفتاح السريري".
  2. دورة تدريبية الكترونية بعنوان "كتابة تقارير المراجعة المهنية.
  3. دورة تدريبية الكترونية بعنوان طرق البحث.
  4. دورة تدريبية في المجلات الطبية البريطانية.
  5. دورة تدريبية في منصة جوفي للمجلات والتعليم العلمي.
  6. دورة في مدخل قواعد بروكويست المختلفة وكيفية الاستفادة منها في الدراسات والأبحاث.
  7. دورة في قاعدة بيانات.EBSCO
  8. دورة تدريبية في قاعدة البيانات للمجلات الأكاديمية. web of science 
  9. دورة تدريبية في إيجاد معلومات البحث الأكثر موائمة لمجال الباحث من على منصة سبرنجر ناتشر.
  10. حضور ورشة تدريبية على منصة الجوفي للتجارب العلمية.
  11. حضور جلسة علمية بعنوان “كيف تدير مجلة علمية ناجحة".
  12. دورة تدريبية في أساسيات الجودة والتقويم والاعتماد.
  13.  دورة تدريبية بعنوان "ممارس جودة أكاديمي".
  14.  دورة تدريبية بعنوان "العمل الجماعي".
  15. دورة تدريبية بعنوان "اضاءات قانونية".
  16. دورة تدريبية بعنوان "التحول الرقمي".
  17.  تقديم دورة عن مرض السكري.
  18.  تقديم دورة عن سلامة المختبر.

الأبحاث العلمية:


1.            Merae Alshahrani M. A glance at the emerging diagnostic biomarkers in the most prevalent genitourinary cancers. Saudi J Biol Sci [Internet]. 2022 Apr 1 [cited 2023 Oct 31];29(4):2072–84. Available from: https://www.sciencedirect.com/science/article/pii/S1319562X22000171
2.            Read M, Baker K, Fletcher A, Thornton C, Alshahrani M, Nieto H, et al. A high-throughput yellow fluorescent protein (YFP) cell-based screen identifies autophagy modulators to increase the effectiveness of radioiodine therapy. In: Endocrine Abstracts [Internet]. Bioscientifica; 2019 [cited 2023 Oct 31]. Available from: https://www.endocrine-abstracts.org/ea/0065/ea0065oc4.1
3.            Mahnashi MH, Muddapur UM, Turakani B, Shaikh IA, Al Awadh AA, Alshahrani MM, et al. A Review on Versatile Eco-Friendly Applications of Microbial Proteases in Biomedical and Industrial Applications. Sci Adv Mater. 2022 Apr 1;14(4):622–37.
4.            S. M. S, Naveen NR, Rao GK, Gopan G, Chopra H, Park MN, et al. A spotlight on alkaloid nanoformulations for the treatment of lung cancer. Front Oncol [Internet]. 2022 Oct 18 [cited 2023 Oct 31];12:994155. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9623325/
5.            Read ML, Brookes K, Thornton CEM, Nieto HR, Fletcher A, de Souza PB, et al. Abstract PO-006: Exploiting non-canonical pathways of NIS regulation to enhance radioiodide uptake and identify predictive markers of recurrence in thyroid cancer. Clin Cancer Res [Internet]. 2021 Apr 15 [cited 2023 Oct 31];27(8_Supplement):PO-006. Available from: https://doi.org/10.1158/1557-3265.RADSCI21-PO-006
6.            Benrahou K, Mrabti HN, Assaggaf HM, Mortada S, Salhi N, Rouas L, et al. Acute and Subacute Toxicity Studies of Erodium guttatum Extracts by Oral Administration in Rodents. Toxins [Internet]. 2022 Nov [cited 2023 Oct 31];14(11):735. Available from: https://www.mdpi.com/2072-6651/14/11/735
7.            Orabi MAA, Lahiq AA, Awadh AAA, Alshahrani MM, Abdel-Wahab BA, Abdel-Sattar ES. Alternative Non-Drug Treatment Options of the Most Neglected Parasitic Disease Cutaneous Leishmaniasis: A Narrative Review. Trop Med Infect Dis [Internet]. 2023 May [cited 2023 Oct 31];8(5):275. Available from: https://www.mdpi.com/2414-6366/8/5/275
8.            Thompson RJ, Fletcher A, Nieto H, Alshahrani M, Baker K, Mueller JW, et al. An investigation into sodium-iodide symporter (NIS) dimerization and its impact on radioiodide uptake in thyroid cancer. In: Endocrine Abstracts [Internet]. Bioscientifica; 2017 [cited 2023 Oct 31]. Available from: https://www.endocrine-abstracts.org/ea/0050/ea0050oc1.4
9.            Palomino-Pacheco M, Rojas-Armas JP, Arroyo-Acevedo JL, Ortiz-S?nchez JM, Justil-Guerrero HJ, Cieza-Macedo EC, et al. Antiulcer Effect of Senna multiglandulosa via Increased Secretion of Mucus and Nonprotein Sulfhydryl Groups in an Experimental Murine Model. Evid Based Complement Alternat Med [Internet]. 2022 Aug 12 [cited 2023 Oct 31];2022:e7570294. Available from: https://www.hindawi.com/journals/ecam/2022/7570294/
10.         Alqahtani A, Alamer E, Mir M, Alasmari A, Alshahrani MM, Asiri M, et al. Bacterial Coinfections Increase Mortality of Severely Ill COVID-19 Patients in Saudi Arabia. Int J Environ Res Public Health [Internet]. 2022 Jan [cited 2023 Oct 31];19(4):2424. Available from: https://www.mdpi.com/1660-4601/19/4/2424
11.         Siddiqui AJ, Patel M, Adnan M, Jahan S, Saxena J, Alshahrani MM, et al. Bacteriocin-Nanoconjugates (Bac10307-AgNPs) Biosynthesized from Lactobacillus acidophilus-Derived Bacteriocins Exhibit Enhanced and Promising Biological Activities. Pharmaceutics [Internet]. 2023 Feb [cited 2023 Oct 31];15(2):403. Available from: https://www.mdpi.com/1999-4923/15/2/403
12.         Alshahrani M, Fletcher A, Thornton C, Brookes K, Nieto H, Thompson R, et al. Biochemical analysis of radioiodine uptake enhancement in endocrine cancer. In: Endocrine Abstracts [Internet]. Bioscientifica; 2018 [cited 2023 Oct 31]. Available from: https://www.endocrine-abstracts.org/ea/0059/ea0059oc2.4
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18.         Siddiqui AJ, Kumar V, Jahan S, Alshahrani MM, Al Awadh AA, Siddiqui MA, et al. Computational insight into structural basis of human ELOVL1 inhibition. Comput Biol Med [Internet]. 2023 May 1 [cited 2023 Oct 31];157:106786. Available from: https://www.sciencedirect.com/science/article/pii/S0010482523002512
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20.         Kumbar VM, Muddapur U, Bin Muhsinah A, Alshehri SA, Alshahrani MM, Almazni IA, et al. Curcumin-Encapsulated Nanomicelles Improve Cellular Uptake and Cytotoxicity in Cisplatin-Resistant Human Oral Cancer Cells. J Funct Biomater [Internet]. 2022 Dec [cited 2023 Oct 31];13(4):158. Available from: https://www.mdpi.com/2079-4983/13/4/158
21.         Imran Qayyum M, Ullah S, Obaidullah, Rashid U, Mahnashi MH, Merae Alshahrani M, et al. Design, synthesis and preclinical evaluations of (s)-2-((s)-1-benzyl-2,5-dioxopyrrolidin-3-yl)-3-(4-isopropylphenyl)-2-methylpropanal (succ-5) as cardioprotective, hepatoprotective and lipid lowering molecule. in-vivo and in-silico approaches. Arab J Chem [Internet]. 2023 Feb 1 [cited 2023 Oct 31];16(2):104504. Available from: https://www.sciencedirect.com/science/article/pii/S1878535222008206
22.         Qasem A, Assaggaf H, Mrabti HN, Minshawi F, Rajab BS, Attar AA, et al. Determination of Chemical Composition and Investigation of Biological Activities of Ocimum basilicum L. Molecules [Internet]. 2023 Jan [cited 2023 Oct 31];28(2):614. Available from: https://www.mdpi.com/1420-3049/28/2/614
23.         Qasem A, Assaggaf H, Montesano D, Khalil Z, Al-Mijalli SH, Baaboua AE, et al. Determination of Chemical Compounds and Investigation of Biological Properties of Matricaria chamomilla Essential Oils, Honey, and Their Mixture. Molecules [Internet]. 2022 Jan [cited 2023 Oct 31];27(18):5850. Available from: https://www.mdpi.com/1420-3049/27/18/5850
24.         Hamad Al-Mijalli S, ELsharkawy ER, Abdallah EM, Hamed M, El Omari N, Mahmud S, et al. Determination of Volatile Compounds of Mentha piperita and Lavandula multifida and Investigation of Their Antibacterial, Antioxidant, and Antidiabetic Properties. Evid Based Complement Alternat Med [Internet]. 2022 Jun 14 [cited 2023 Oct 31];2022:e9306251. Available from: https://www.hindawi.com/journals/ecam/2022/9306251/
25.         Thompson RJ, Fletcher A, Brookes K, Nieto H, Alshahrani MM, Mueller JW, et al. Dimerization of the Sodium/Iodide Symporter. Thyroid® [Internet]. 2019 Oct [cited 2023 Oct 31];29(10):1485–98. Available from: https://www.liebertpub.com/doi/full/10.1089/thy.2019.0034
26.         Nieto H, Thornton C, Fletcher A, Menezes AN de, Brookes K, Alshahrani M, et al. Driver events in thyroid cancer recurrence. In: Endocrine Abstracts [Internet]. Bioscientifica; 2019 [cited 2023 Oct 31]. Available from: https://www.endocrine-abstracts.org/ea/0065/ea0065oc4.6
27.         Idrissi ZLE, El Moudden H, Mghazli N, Bouyahya A, Guezzane CE, Alshahrani MM, et al. Effects of Extraction Methods on the Bioactivities and Nutritional Value of Virginia and Valencia-Type Peanut Oil. Molecules [Internet]. 2022 Jan [cited 2023 Oct 31];27(22):7709. Available from: https://www.mdpi.com/1420-3049/27/22/7709
28.         Faloye KO, Bekono BD, Fakola EG, Ayoola MD, Bello OI, Olajubutu OG, et al. Elucidating the Glucokinase Activating Potentials of Naturally Occurring Prenylated Flavonoids: An Explicit Computational Approach. Molecules [Internet]. 2021 Jan [cited 2023 Oct 31];26(23):7211. Available from: https://www.mdpi.com/1420-3049/26/23/7211
29.         Manivannan S, Kocbiyik M, Alshahrani M, El-Asrag ME, Zha L, Brookes K, et al. Elucidating the mechanisms via which the proto-oncogene PBF stimulates cell motility in thyroid tumour progression: 71st Annual Meeting of the British Thyroid Association<br/>. Thyroid Res. 2023 Jul 11;16(S1):6–6.
30.         Alshahrani MM, Albogami HA, Asiri AA, Al haydhah KS, Aldeailej IM, Aldehaim MA, et al. Epidemiological Trends of Acute Chemical Poisoning among Children over a Recent Three-Year Period in Saudi Arabia. Children [Internet]. 2023 Feb [cited 2023 Oct 31];10(2):295. Available from: https://www.mdpi.com/2227-9067/10/2/295
31.         Alamri MA, Alawam AS, Alshahrani MM, Kawsar SMA, Prinsa, Saha S. Establishing the Role of Iridoids as Potential Kirsten Rat Sarcoma Viral Oncogene Homolog G12C Inhibitors Using Molecular Docking; Molecular Docking Simulation; Molecular Mechanics Poisson–Boltzmann Surface Area; Frontier Molecular Orbital Theory; Molecular Electrostatic Potential; and Absorption, Distribution, Metabolism, Excretion, and Toxicity Analysis. Molecules [Internet]. 2023 Jan [cited 2023 Oct 31];28(13):5050. Available from: https://www.mdpi.com/1420-3049/28/13/5050
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34.         Kazmi SA, Rauf A, Alshahrani MM, Awadh AAA, Iqbal Z, Soltane R, et al. Hepatitis B among University Population: Prevalence, Associated Risk Factors, Knowledge Assessment, and Treatment Management. Viruses [Internet]. 2022 Sep [cited 2023 Oct 31];14(9):1936. Available from: https://www.mdpi.com/1999-4915/14/9/1936
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37.         Orabi MAA, Alshahrani MM, Sayed AM, Abouelela ME, Shaaban KA, Abdel-Sattar ES. Identification of Potential Leishmania N-Myristoyltransferase Inhibitors from Withania somnifera (L.) Dunal: A Molecular Docking and Molecular Dynamics Investigation. Metabolites [Internet]. 2023 Jan [cited 2023 Oct 31];13(1):93. Available from: https://www.mdpi.com/2218-1989/13/1/93
38.         Elouafy Y, El Yadini A, El Moudden H, Harhar H, Alshahrani MM, Awadh AAA, et al. Influence of the Extraction Method on the Quality and Chemical Composition of Walnut (Juglans regia L.) Oil. Molecules [Internet]. 2022 Jan [cited 2023 Oct 31];27(22):7681. Available from: https://www.mdpi.com/1420-3049/27/22/7681
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41.         Thornton CE, Fletcher A, Nieto H, Brookes K, Alshahrani M, Read M, et al. Investigating the mechanism behind sodium-iodide symporter trafficking by the small GTPase ARF4. In: Endocrine Abstracts [Internet]. Bioscientifica; 2019 [cited 2023 Oct 31]. Available from: https://www.endocrine-abstracts.org/ea/0065/ea0065p393
42.         Aboulaghras S, Piancatelli D, Taghzouti K, Balahbib A, Alshahrani MM, Al Awadh AA, et al. Meta-Analysis and Systematic Review of HLA DQ2/DQ8 in Adults with Celiac Disease. Int J Mol Sci [Internet]. 2023 Jan [cited 2023 Oct 31];24(2):1188. Available from: https://www.mdpi.com/1422-0067/24/2/1188
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